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The evidence suggests that an interaction between high folate and low vitamin B-12 does in fact exist, that the biochemical response to this interaction is paradoxical, and that it represents a novel (acquired) vitamin B-12 deficiency state with a specific etiology

doi: 10.1016/J.IT.2016.01.002 246 BoneRNOyebamijiOTalwareSSelvarajSKrishnanPSyedFet al

Look beyond the scale: Measurements, energy, and appetite changes matter

But, the good news is that within two weeks of cutting out all added sugars and artificial sweeteners, the hold has already started to break and the appeal of sweet food has generally reduced significantly