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ZSTK474 0419 Pretreatment of adipocytes with GF-109203X

ZSTK474 0419 Pretreatment of adipocytes with GF-109203X

Name: ZSTK474 0419 Pretreatment of adipocytes with GF-109203X
Brand: buntepalette-gmbh.de
SKU: 22487744272
Price: 100.00 USD
Availability: InStock
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SKU: 22487744272

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USD100.00 USD146.00

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ZSTK474 0419 Pretreatment of adipocytes with GF-109203XZSTK474 is a novel orally applicable phosphoinositide 3 kinase specific inhibitor that strongly inhibits cancer cell proliferation. Combination treatment using X rays then ZSTK474 given orally for 8 days, starting 24h post irradiation, significantly enhanced cell growth inhibition. The combined effect was also observed for clonogenic survival with continuous ZSTK474 treatment. Western blot analysis showed enhanced phosphorylation of Akt and GSK 3 by X

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Description

Pretreatment of adipocytes with GF-109203X (5 microM) reduced GSK-3 activity in total cell lysates

[Epub ahead of print] PubMed PMID: 25404465

Nishimura H

UNII-R1ZW9H43ZJ

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