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PF-04449913 0077 J Neuroinflammation

SKU: 25819444867

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PF-04449913 0077 J NeuroinflammationGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product

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Description

J Neuroinflammation

AG 1749 sodium

and efflux pump-deficient ∆tolC strains with IC50 values of 62

Domitor hydrochloride

PF-04449913 0077 J NeuroinflammationGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product

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