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Chelators can strip copper from the GHK-Cu component, and reducing agents may affect peptide stability during prolonged exposure in the same buffer

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of this proposed rule, we are proposing a modification to the Prescriber-Pharmacy Methodology whereby all claims for Part D drugs dispensed to beneficiaries identified as having ADAP supplemental coverage would be treated as 340B-eligible and excluded from Part D inflation rebate calculations, with safeguards to prevent double-counting of units already identified under the existing methodology