Rat Leukemia Inhibitory Factor Receptor, LIFR ELISA Kit, 96T Culture Media Clathrin (see MIM 118955)-mediated endocytosis

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids

It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity

and can induce apoptosis and weakly activate the NF-kappaB transcription factor

It induces the expression of class II MHC molecules on resting B-cells

Rat Leukemia Inhibitory Factor Receptor, LIFR ELISA Kit, 96T Culture Media Clathrin (see MIM 118955)-mediated endocytosisSignal transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity).