Rat Cyclin-dependent Kinase 4, CDK-4 ELISA Kit, 96T Drying & Desiccation Pseudogenes of this gene are

Pseudogenes of this gene are found on chromosomes 9 and X

The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate

This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates

Elevated expression of alpha-B crystallin occurs in many neurological diseases

Rat Cyclin-dependent Kinase 4, CDK-4 ELISA Kit, 96T Drying & Desiccation Pseudogenes of this gene areSer Thr kinase component of cyclin D CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell cycle during G(1) S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in