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Because of the harmful effects of reactive oxygen species (ROS) and free radicals, oxidative stress is one of the key mechanisms that drive telomere shortening (Epel et al., 2004

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Lancet Diabetes Endocrinol 7(10):776785 Muskiet MHA, Smits MM, Morsink LM, Diamant M (2014) The gutrenal axis: do incretin-based agents confer renoprotection in diabetes