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Estradiol signaling mediates gender difference in visceral adiposity via autophagy

These effects are attributed to their content of key growth factors such as platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), insulin-like growth factor-1 (IGF-1), epidermal growth factor (EGF), and transforming growth factor beta (TGF-) [28] all of which are known to influence angiogenesis, cell survival, stem cell proliferation, and tissue remodeling [29,30,31]