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As mentioned above, healthy RPE relies upon mitochondrial oxidative phosphorylation to conserve and shuttle glucose to photoreceptors

doi:10.1159/000118012 van Kammen DP, Widerlv E, Neylan TC, Ekman R, Kelley ME, Mouton A, Peters JL

Long-term extension data from an open-label follow-up study showed no new safety signals with continued on-demand use beyond the initial 24-week trial