CENPT Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing and some of these variants

and some of these variants have been shown to encode more than one isoform

and cardiovascular function

The encoded protein consists of four N-terminal immunoglobulin-like domains| six fibronectin type III domains| a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC

A pseudogene of this gene is also present on chromosome 8q21

CENPT Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing and some of these variantsThe centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006