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Tafazzin Polyclonal Antibody, 50ul Peptide Modification The protein encoded by this

SKU: 43768448608

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Tafazzin Polyclonal Antibody, 50ul Peptide Modification The protein encoded by thisTAZ (tafazzin) encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in TAZ have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is

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Description

The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA

The long form is expressed in steroidogenic tissues such as testis

The CARL-1 monoclonal antibody reacts with human TWEAK

Multiple alternatively spliced variants have been identified

Tafazzin Polyclonal Antibody, 50ul Peptide Modification The protein encoded by thisTAZ (tafazzin) encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in TAZ have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is

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