Metformin hydrochloride 0285 Treatments with 2-HBA cause cell

Treatments with 2-HBA cause cell cycle arrest and apoptosis in both L1210 wild type cells and their Y8 drug-resistant counterparts in a concentration-dependent manner

Chemical Name: (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1

2'-[2H]pyran]-3

Epub 2015 Mar 14

Metformin hydrochloride 0285 Treatments with 2-HBA cause cellMetformin hydrochloride (1,1 Dimethylbiguanide hydrochloride) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy[1]. Product information CAS Number: 1115 70 4 Molecular Weight: 165. 62 Formula: C4H12ClN5 Synonym: ADX 155 EFB 0027 EX 404 La 6023 SMP 862 ADX 155 EFB 0027 EX 404 La 6023 SMP 862 ADX155 EFB0027 EX404