PAK Gamma Polyclonal Antibody, 100ul[BT-AP06901] Apoptosis & Autophagy Mutations in this gene result

Mutations in this gene result in autosomal recessive Charcot-Marie-Tooth disease type 4C

The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin

GO annotations related to this gene include receptor binding and GABA receptor binding

Pseudogenes of this gene are present on chromosomes 1| 3| 9| 12 and 20| and on the X chromosome

PAK Gamma Polyclonal Antibody, 100ul[BT-AP06901] Apoptosis & Autophagy Mutations in this gene resultThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by PAK2 is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role in