MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor =

Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor

The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics

RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi

tissue specificity:Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia

MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays Catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor =This gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation