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INFOGRAPHIC BRIEFS Infographic Brief 1 Placement: After ## How GHK-Cu Is Thought to Work Title: GHK-Cu Mechanism and Skin Biology Pathways Purpose: Explain how GHK-Cu is discussed in relation to copper binding, fibroblast activity, collagen synthesis, extracellular matrix remodeling, inflammation, and wound repair mechanisms

In vitro studies using adipocyte precursor cell lines have investigated how this fragment influences adipogenic transcription factor expression, including PPAR and C/EBP, which are key regulators of the adipocyte differentiation programme